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. 2020 Nov 5;8:578036. doi: 10.3389/fcell.2020.578036

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Copyright © 2020 Uchida, Ferdousi, Zheng, Oda and Isoda.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Volcano plots showing DEGs (fold change >2, p value < 0.05) between (A) D10 isorhamnetin-treated and D0 control hAECs, and (B) D10 isorhamnetin-treated and D10 control hAECs. The Y-axis corresponds to –log10 p-value, and the X-axis displays linear fold change. The red dots represent the upregulated genes; the green dots represent the downregulated genes. (C) Bar graph showing number of DEGs in each treatment pair. (D) Venn diagram showing common and unique sets of DEGs between each exposure. Blue circle denotes DEGs between D10 and D0 controls; red circle denotes DEGs between D10 isorhamnetin-treated and D0 control hAECs. Iso, Isorhamnetin.