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. 2020 Nov 5;8:578036. doi: 10.3389/fcell.2020.578036

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Copyright © 2020 Uchida, Ferdousi, Zheng, Oda and Isoda.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Bar graph showing significantly downregulated GO in D10 isorhamnetin-treated hAECs compared to D10 control. Heatmaps showing signal intensities (log2) of genes (from microarray analysis) related to (B) Transdifferentiation, (C) Cholangiocyte, and (D) Colon. (E) Relative expression levels of genes to trace transdifferentiation. *P < 0.05, **P < 0.01, ns: not significant.