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. Author manuscript; available in PMC: 2021 Dec 15.
Published in final edited form as: Biol Psychiatry. 2020 May 19;88(12):910–921. doi: 10.1016/j.biopsych.2020.05.011

Figure 7. MG depletion reduces GABAergic transmission in the CeA even after alcohol dependence.

Figure 7.

(a) Representative sIPSC traces and scaled averages in the central nucleus of the amygdala (CeA) neurons from Control Diet or microglia (MG) Depletion mice that were alcohol-dependent (Dep, on left) or non-dependent (Non-Dep, on right). (b-e) MG depletion significantly decreased the mean sIPSC frequency (b), amplitude (c) and decay time (e) in CeA neurons of Dep and Non-Dep mice (n=42–50 cells from 5 mice/group). Data are presented as mean±SEM values; # P<0.05, ## P<0.01 or ### P<0.001 main effect of diet by two-way ANOVA.