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. 2020 Nov 18;10:20056. doi: 10.1038/s41598-020-77167-y

Table 2.

Summary of the AUC, sensitivity, and specificity for CRP, CA125, and HE4 in the diagnosis of EOC.

AUC 95% CI Sensitivity (%) Specificity (%)
CRP 0.89 0.84–0.94 82.4 88.9
CA125 0.93 0.89–0.96 79.1 88.9
HE4 0.71 0.63–0.79 62.6 81.4
CRP + CA125 0.95 0.92–0.98 86.8 90.1
CRP + HE4 0.89 0.84–0.94 82.4 87.6
CA125 + HE4 0.93 0.89–0.96 78.0 87.6
CRP + CA125 + HE4 0.96 0.92–0.98 87.9 91.3