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. 2020 Nov 18;10:20092. doi: 10.1038/s41598-020-77088-w

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Comparison of AS-OCT quantification parameters between Gram−ve, Gram+ve and microbiology negative bacterial keratitis. (a) There was a significant difference in presentation corneal thickness between Gram−ve and Gram+ve groups, and between Gram−ve and microbiology negative groups, but not between Gram+ve and microbiology negative groups. (b) There was a significant difference in presentation infiltrate thickness between Gram−ve and Gram+ve BK, and Gram−ve and microbiology negative BK, but not between Gram+ve and microbiology negative BK (p = 1.0). (c) There was a significant difference in corneal tissue swelling between Gram−ve and Gram+ve groups, and Gram−ve and microbiology negative groups, but not between Gram+ve and microbiology negative groups. (d) There was a borderline significant difference in corneal tissue loss between Gram−ve and Gram+ve BK (p = 0.12), a significant difference between Gram−ve and microbiology negative BK, and no significant difference between Gram+ve and microbiology negative BK.