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. 2020 Nov 5;23(11):101769. doi: 10.1016/j.isci.2020.101769

Figure 3.

Figure 3

Overall Information of an AD Disease Data set (AD00103) and UMAP Plot of the Cell Types and Expression Distribution of Gene MBP in This Data set

(A) Overall information on an AD disease data set (AD00103). It includes the information of species, brain region, condition, gender, age, number of control-like and AD-associated cells, data set source, and data sets from the same experiment.

(B) UMAP plot colored by cell type on this AD disease data set. We identified seven cell types, i.e. astrocytes, endothelial cells, excitatory neurons, inhibitory neurons, microglia, oligodendrocytes, and oligodendrocyte precursor cells.

(C) UMAP plot of expression distribution of oligodendrocyte marker gene MBP in the same data set. The darker the color is in this UMAP, the higher the expression value of the gene. Adj. p-value: wilcoxon rank sum test, Bonferroni corrected.