Figure 6.

ProAgio plus Gem further reduces intratumoral collagen and CAPaSC. (A and B) Representative images of Sirius red staining (A) and IHC staining of α-SMA (B) in tumor sections from GEM-KPC and OrKPC mice treated with the indicated agents. (C–F) Quantitative analyses of Sirius red stain area (Sirius red⁺ area %) (C and D) and IHC α-SMA stain area (α-SMA⁺ area %) (E and F) in sections of tumors from GEM-KPC and OrKPC mice treated by the indicated agents. (F) Error bars represent means ± SEM. ∗P < .05, ∗∗P < .01, ∗∗∗P < .001, ∗∗∗∗P < .0001. n.s., not significant.