Table 2.

For all structures and hemispheres, first the mean volume ± standard deviation (std) in millimeter of reference and the four automated segmentation software

Method	Left Caudate			Right Caudate
N = 32	Volume	ICC	DSC	Volume	ICC	DSC
Reference	3.99 ± 0.64			3.98 ± 0.60
FSL-FIRST	3.46 ± 0.45	0.69	0.84 ± 0.04	3.53 ± 0.49	0.81	0.84 ± 0.04
FreeSurfer	3.55 ± 0.52	0.74	0.76 ± 0.09	3.75 ± 0.58	0.68	0.77 ± 0.09
GIF	3.52 ± 0.42	0.50	0.83 ± 0.04	3.73 ± 0.47	0.60	0.83 ± 0.05
volBrain	3.55 ± 0.55	0.85	0.83 ± 0.07	3.57 ± 0.54	0.86	0.83 ± 0.07

	Left Putamen			Right Thalamus
	Volume	ICC	DSC	Volume	ICC	DSC
Reference	4.79 ± 0.79			4.65 ± 0.73
FSL-FIRST	4.85 ± 0.73	0.94	0.88 ± 0.03	4.83 ± 0.79	0.93	0.87 ± 0.04
FreeSurfer	4.60 ± 0.88	0.94	0.81 ± 0.08	4.66 ± 0.88	0.96	0.81 ± 0.07
GIF	4.37 ± 0.70	0.98	0.80 ± 0.03	4.34 ± 0.65	0.92	0.81 ± 0.03
volBrain	4.09 ± 0.65	0.77	0.84 ± 0.06	4.04 ± 0.60	0.80	0.84 ± 0.06

	Left Thalamus			Right Thalamus
	Volume	ICC	DSC	Volume	ICC	DSC
Reference	6.83 ± 1.19			6.80 ± 1.21
FSL-FIRST	7.87 ± 1.01	0.76	0.82 ± 0.05	7.69 ± 0.98	0.79	0.83 ± 0.05
FreeSurfer	7.32 ± 1.10	0.80	0.77 ± 0.08	6.93 ± 1.01	0.95	0.78 ± 0.08
GIF	5.81 ± 0.76	0.72	0.77 ± 0.04	5.67 ± 0.68	0.64	0.76 ± 0.04
volBrain	5.47 ± 1.01	0.68	0.80 ± 0.07	5.39 ± 0.98	0.67	0.80 ± 0.07

Second, the intra-class correlation coefficient (ICC) and mean dice similarity coefficient (DSC) ± std between the reference and the segmentation of the automated segmentation software. N = amount of subjects