. 2020 Nov 19;22(12):76. doi: 10.1007/s11936-020-00871-5

Table 2.

Diagnostic Criteria criteria for Cardiac cardiac Sarcoidosis sarcoidosis Proposed proposed ion the 2014 Heart Rhythm Society Consensus consensus Statementstatement

Histological diagnosis* (“definite”)	Clinical diagnosis* (“probable”)
CS diagnosed in the presence of noncaseating granuloma on histological examination	(a) Histology of extra-cardiac sarcoidosis AND (b) One or more of the following: •Steroid ± immunosuppressant responsive cardiomyopathy or atrioventricular block •Unexplained reduced EF < 40% •Unexplained sustained (spontaneous or induced) VT •Mobitz type II 2nd degree or 3rd degree heart block •Patchy uptake on dedicated cardiac PET (in a pattern consistent with CS) •Late gadolinium enhancement (LGE) on CMR (in a pattern consistent with CS) •Positive gallium uptake

Histological diagnosis* (“definite”)

Clinical diagnosis* (“probable”)

CS diagnosed in the presence of noncaseating granuloma on histological examination

(a) Histology of extra-cardiac sarcoidosis

AND

(b) One or more of the following:

•Steroid ± immunosuppressant responsive cardiomyopathy or atrioventricular block

•Unexplained reduced EF < 40%

•Unexplained sustained (spontaneous or induced) VT

•Mobitz type II 2nd degree or 3rd degree heart block

•Patchy uptake on dedicated cardiac PET (in a pattern consistent with CS)

•Late gadolinium enhancement (LGE) on CMR (in a pattern consistent with CS)

•Positive gallium uptake

*No alternative cause identified—including negative organismal strains (fungal)