Table III.
Secondary outcomes.
| Secondary outcomes | |
|---|---|
| Exercise test | • Time (s) to 1 mV ST depression |
| • Maximum ST-segment deviation (mV) | |
| • Time (s) to 75% of max age-related heart rate during exercise | |
| • Metabolic equivalent (METs) | |
| • The DUKE Score70 | |
| Health Status Questionnaires | • Seattle Angina Questionnaire (SAQ)43 |
| • Illness perception • (Brief IPQ)48 | |
| • Anxiety/depression • (PHQ4)50 | |
| • Treatment satisfaction • (TSQM)49 | |
| • EQ-5D-5L47 | |
| Safety | • Frequency and severity of severe adverse events (SAEs) |
| Feasibility | • Participant withdrawal rate |
| Efficacy | • Pharmacokinetics • Pharmacodynamics |
| Exploratory endpoints/outcomes | |
| Patient-Reported Outcome Measures (PROMS) | • Angina diary |