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The gut–muscle axis led to sarcopenia via regulating the processes of mitochondrial dysfunction and modulation of host gene expression. (A) AMP-activated protein kinase (AMPK) and carnitine palmitoyl transferase-1 (CPT-1) are increased. (B) Mitochondrial dysfunction. (C) Autophagy-lysosomal pathway related proteins reduced. (D) Cell signaling pathway regulation process.
