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. 2020 Sep 3;61(6):832–841. doi: 10.1093/jrr/rraa065

Table 1.

CI of irradiation with cisplatin in the three cell lines. Data are presented as the mean of three determinations. The sensitizing effect is <1.0 in the CI [17]

Cell Cisplatin (μM) X-Ray + cisplatin Proton + cisplatin
Dose (Gy) CI Dose (GyE) CI
HSG 0.25 2 1.04 2 1.01
0.5 1.12 1.12
1.5 1.1 0.99
2.5 0.82 0.86
0.25 5 0.84 5 0.86
0.5 0.79 0.83
1.5* 0.48 0.68
2.5 0.33 0.39
EMT6 0.25 2 1.21 2 1.47
0.5 1.28 1.23
1.5* 1 0.89
2.5* 0.73 0.54
0.25 5 0.94 5 1.04
0.5 0.89 0.94
1.5 0.68 0.62
2.5* 0.55 0.4
V79 0.25 2 1 2 0.99
0.5 1.19 0.98
1.5* 1.23 0.67
2.5* 1.08 0.61
0.25* 5 0.97 5 0.8
0.5* 0.88 0.78
1.5* 0.88 0.63
2.5* 0.74 0.38

*P < 0.05 between X-ray + cisplatin and proton + cisplatin.