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Effect of APOBEC3B on DNA damage repair after IR. HepG2, A3BKO, Mock and A3B cells were irradiated with 5 Gy X-ray, and stained with Alexa Fluor 488-conjugated anti-γ-H2AX Ab and Hoechst 33342 at the indicated times. Cell images were captured and the numbers of γ-H2AX foci per nucleus were analyzed using an Operetta CLS High-Content System. Data are presented as mean ± SEM; *P < 0.05 vs control (HepG2); **P < 0.01 vs control (HepG2 or Mock).
