TABLE 2.
Logistic regression analysis for clinical and imaging predictors of iRBD.
| Variables |
Univariate |
Multivariable |
||
| OR (95% CI) | P-value | OR (95% CI) | P-value | |
| Clinical variables | ||||
| Age, years | 1.05 (0.99–1.12) | 0.082 | – | – |
| Sex, male | 0.49 (0.19-1.30) | 0.153 | – | – |
| Smoking | 2.25 (0.67–7.61) | 0.192 | – | – |
| Hypertension | 1.63 (0.57–4.70) | 0.365 | – | – |
| Hyperlipidaemia | 1.29 (0.27–6.26) | 0.752 | – | – |
| Diabetes mellitus | 0.29 (0.03–2.98) | 0.300 | – | – |
| MoCA | 0.89 (0.78–1.01) | 0.080 | 0.79 (0.66–0.94) | 0.008 |
| Imaging findings | ||||
| CSO-EPVS | 1.07 (1.00–1.14) | 0.041 | 1.10 (1.00–1.21) | 0.048 |
| BG-EPVS | 1.13 (1.01–1.27) | 0.030 | – | – |
| SN-EPVS | 1.47 (1.02–2.12) | 0.037 | – | – |
| BS-EPVS | 1.50 (1.06–2.13) | 0.022 | 1.95 (1.18–3.23) | 0.010 |
| WMH score | 1.05 (0.77–1.44) | 0.760 | – | – |
OR, odds ratio; MoCA, Montreal Cognitive Assessment; EPVS, enlarged perivascular spaces; CSO, centrum semiovale; BG, basal ganglia; SN, substantia nigra; BS, brainstem; WMH, white matter hyperintensity. P-value < 0.05.