Skip to main content
. 2020 Nov 18;1(11):100254. doi: 10.1016/j.xcrp.2020.100254

Figure 2.

Figure 2

Cal@MIL-101(Cr) and Cal@UiO-66 Are Internalized by Cells and Enhance the Delivery of Calcein

(A–D) Flow cytometry of free calcein versus Cal@MOF in HEK-293 cells, for (A) Cal@MIL-101(Cr) and (B) Cal@UiO-66, and in MCF-7 cells, for (C) Cal@MIL-101(Cr) and (D) Cal@UiO-66, measured 24 and 72 h post-administration. The concentration that was used for free calcein corresponds to the amount of calcein loaded in Cal@MIL-101(Cr) and Cal@UiO-66, respectively. The data are presented as means ± SEMs; 1-way ANOVA with Sidak’s test (n = 3).

(E and F) Cell viability assessed with flow cytometry in (E) HEK-293 and (F) MCF-7 cells, 24 and 72 h post-MOF administration with Cal@MIL-101(Cr) and Cal@UiO-66. The data are presented as means ± SEMs; 1-way ANOVA with Dunnett’s test (n = 3).

∗p ≤ 0.05, ∗∗p ≤ 0.01, ∗∗∗p ≤ 0.001, and ∗∗∗∗p ≤ 0.0001.