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. 2020 Nov 5;10:588195. doi: 10.3389/fcimb.2020.588195

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Copyright © 2020 Pan, Grandgirard and Leib

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of inflammatory parameters in the brain parenchyma of infected animals. At 24 hpi (A) and 42 hpi (B), the protein levels of several inflammatory parameters were significantly decreased in infected animals treated with CRO/JWH-13 (blue bars) compared to animals treated with CRO only (orange bars). Only few inflammatory parameters could be detected in uninfected animals (white bars). (PM+ CRO, n = 6; PM+ CRO/JWH133, n = 6; PM-, n = 4; Multiple t test with Holm-Sidak correction; **p < 0.01; ***p < 0.001; ****p < 0.0001).