Table 2.
Regions showing significantly decreased pairwise FC in patients with ESRD compared with HCs.
| ROI region | Connected brain ROI region | t-value |
|---|---|---|
| ESRD vs. HCs | ||
| NBS correction (p < 0.05) | ||
| PCC | aMPFC | −2.029 |
| pIPL | −3.040 | |
| Rsp | −2.205 | |
| aMPFC | dMPFC | −2.191 |
| TPJ | −2.058 | |
| Rsp | −3.387 | |
| dMPFC | TPJ | −3.040 |
| pIPL | Rsp | −2.329 |
| PHC | −2.559 | |
FC, functional connectivity; ESRD, end-stage renal disease; HCs, healthy controls; NBS, network-based statistic; PCC, posterior cingulate cortex; aMPFC, anterior medial prefrontal cortex; dMPFC, dorsal medial prefrontal cortex; TPJ, temporal parietal junction; Rsp, retrosplenial cortex; pIPL, posterior inferior parietal lobule; PHC, parahippocampal cortex.