Age (years) |
37 (±12) |
39 (±15) |
46 (±16) |
35 (±9) |
<0.001 |
Gender (male) |
477 (86.9%) |
15 (53.6%) |
51 (51.0%) |
411 (97.6%) |
<0.001 |
Ethnicity |
|
|
|
|
<0.001 |
Chinese |
91 (16.5%) |
16 (57.1%) |
49 (49.0%) |
26 (6.1%) |
|
Malay |
34 (6.1%) |
1 (3.6%) |
20 (20.0%) |
13 (3.1%) |
|
Indian |
199 (36.0%) |
1 (3.6%) |
17 (17.0%) |
181 (42.6%) |
|
Bangladeshi |
175 (31.6%) |
0 (0%) |
1 (1.0%) |
174 (40.9%) |
|
Others |
55 (9.9%) |
11 (37.9%) |
13 (13.0%) |
31 (7.3%) |
|
|
Medical comorbidities |
Prior history of hypertension |
53 (12.3%) |
2 (12.5%) |
30 (57.7%) |
21 (5.8%) |
<0.001 |
Prior history of hyperlipidaemia |
34 (8.1%) |
6 (33.3%) |
23 (51.1%) |
5 (1.4%) |
<0.001 |
Prior history of diabetes mellitus |
21 (5.1%) |
1 (6.3%) |
15 (37.5%) |
5 (1.4%) |
<0.001 |
Prior history of asthma |
6 (1.5%) |
1 (5.9%) |
2 (5.6%) |
3 (0.8%) |
0.024 |
No previous medical conditions |
367 (90.4%) |
11 (68.8%) |
19 (55.9%) |
337 (94.7%) |
<0.001 |
Newly-diagnosed hypertension |
12 (2.9%) |
2 (12.5%) |
1 (2.9%) |
9 (2.5%) |
0.068 |
Newly-diagnosed diabetes mellitus |
8 (2.0%) |
0 (0.0%) |
0 (0.0%) |
8 (2.2%) |
0.560 |
|
Clinical profile |
Asymptomatic illness |
66 (11.9%) |
0 (0.0%) |
3 (3.0%) |
63 (14.8%) |
0.001 |
Day of illness at presentation |
3.5 (±5.1) |
3.8 (±2.5) |
5.8 (±5.2) |
2.9 (±5.0) |
<0.001 |
Length of days with fever |
1.2 (±2.4) |
2.0 (±2.4) |
1.6 (±2.7) |
1.1 (±2.3) |
0.025 |
Admission temperature (oC) |
37.7 (±3.9) |
37.4 (±0.9) |
37.3 (±0.7) |
37.8 (±4.4) |
0.480 |
Systolic blood pressure (mmHg) |
130 (±17) |
127 (±16) |
127 (±18) |
131 (±17) |
0.078 |
Diastolic blood pressure (mmHg) |
81 (±12) |
74 (±13) |
74 (±12) |
83 (±11) |
<0.001 |
Oxygen saturation (%) |
98 (±3) |
97 (±7) |
97 (±4) |
98 (±1) |
<0.001 |
Pulse rate (/min) |
94 (±19) |
89 (±15) |
89 (±14) |
96 (±20) |
0.002 |
Respiratory rate (/min) |
19 (±7) |
19 (±2) |
19 (±3) |
19 (±6) |
0.888 |
|
Baseline laboratory investigations |
Total white cell count (×109/L) |
6.5 (±2.2) |
6.9 (±3.9) |
6.2 (±2.7) |
6.5 (±1.9) |
<0.001 |
Absolute neutrophil count (×109/L) |
4.18 (±7.9) |
4.89 (±3.91) |
3.90 (±2.37) |
4.19 (±8.88) |
0.849 |
Absolute lymphocyte count (×109/L) |
1.90 (±2.02) |
1.33 (±0.62) |
1.59 (±1.01) |
2.00 (±2.22) |
0.062 |
Haemoglobin (g/dL) |
14.9 (±1.6) |
14.1 (±2.1) |
13.4 (±1.6) |
15.2 (±1.4) |
0.119 |
Platelet count (×109/L) |
228 (±60) |
204 (±48) |
230 (±69) |
229 (±59) |
0.029 |
Haematocrit (%) |
45 (±23) |
42 (±6) |
40 (±5) |
47 (±6) |
0.007 |
Sodium (mmol/L) |
138 (±3) |
137 (±3) |
137 (±4) |
138 (±2) |
0.679 |
Creatinine (mmol/L) |
79 (±30) |
82 (±27) |
81 (±64) |
79 (±14) |
0.038 |
Albumin (g/L) |
43 (±17) |
40 (±7) |
39 (±4) |
44 (±18) |
<0.001 |
AST (units/L) |
38 (±48) |
83 (±21) |
32 (±19) |
37 (±24) |
0.001 |
ALT (units/L) |
46 (±44) |
60 (±130) |
29 (±20) |
48 (±38) |
0.009 |
LDH (units/L) |
436 (±423) |
691 (±110) |
459 (±259) |
418 (±377) |
<0.001 |
C-reactive protein (mg/L) |
14 (±27) |
33 (±46) |
24 (±37) |
11 (±23) |
<0.001 |
Ferritin (ug/L) |
179 (±216) |
404 (±459) |
234 (±392) |
161 (±143) |
<0.001 |