Table 1.
Study Sample Characteristics by Apnea-Hypopnea Index Quartile
| Characteristic | Events per Hour |
|||
|---|---|---|---|---|
| < 3.1 |
3.2-10.6 |
10.7-24.6 |
≥ 24.7 |
|
| (n = 30) | (n = 29) | (n = 30) | (n = 29) | |
| Demographics | ||||
| Sex, male | 36.7 | 55.2 | 70 | 79.3a |
| Race, white | 90 | 93.1 | 80 | 82.8 |
| Age, y | 36.4 (1.9) | 44.8 (2.4) | 49.3 (2.0) | 52.5 (1.7)b |
| Body composition | ||||
| BMI, kg/m2 | 26.3 (0.9) | 29.2 (1.3) | 29.8 (0.8) | 32.4 (1.0)b |
| Waist circumference, cm | 82.7 (2.1) | 90.2 (2.6) | 94.1 (1.9) | 105.2 (2.6)b |
| Percent body fat, % | 30.7 (2.0) | 33.0 (1.8) | 29.9 (1.7) | 34.8 (1.4) |
| Actigraphy monitoring | ||||
| Usual time in bed, h | 7.8 (0.2) | 7.6 (0.2) | 7.8 (0.1) | 7.5 (0.2) |
| Sleep duration, h | 7.2 (0.2) | 7.0 (0.2) | 7.3 (0.1) | 6.5 (0.2) |
| Polysomnography | ||||
| Total sleep time, h | 6.7 (0.3) | 6.9 (0.2) | 6.9 (0.2) | 6.4 (0.2) |
| Stage N1 sleep, % | 7.4 (0.7) | 10.1 (1.0) | 11.0 (1.1) | 15.0 (1.8)b |
| Stage N2 sleep, % | 55.7 (1.5) | 57.2 (1.5) | 62.3 (1.4) | 63.0 (2.1)b |
| Slow wave sleep (N3), % | 13.6 (1.4) | 12.7 (1.1) | 7.6 (0.9) | 5.1 (1.2)b |
| REM sleep, % | 23.3 (0.9) | 20.1 (1.1) | 19.1 (1.3) | 16.9 (1.2)b |
| Arousal index, No./h | 11.1 (0.8) | 14.2 (1.5) | 20.3 (1.3) | 45.1 (4.1)b |
| ΔSpo2, % | 3.2 (0.2) | 3.8 (0.2) | 3.7 (1.7) | 6.4 (0.8)b |
| Serum measurements | ||||
| Fasting glucose, mg/dL | 93.1 (1.3) | 98.6 (1.5) | 98.5 (1.6) | 103.0 (1.8)b |
| Fasting FFA, μM | 479.5 (37.1) | 577.5 (96.8) | 457.6 (35.4) | 482.3 (38.0) |
Values are reported are either percentages or means (SE). AHI = apnea-hypopnea index; ΔSpo2 = average oxyhemoglobin desaturation; REM = rapid eye movement.
a
P < .02 for comparisons across AHI groups (P values determined by analysis of variance).
b
P < .001 for comparisons across AHI groups (P values determined by analysis of variance).