Table 1.

Number of Variants Concordant and Discordant with Initial Laboratory Classifications

	Initial Laboratory Classification
	P	LP	VUS	LB	B
Classification by Other Two Laboratories
P	10	2	3	0	0
LP	5	1	5	0	0
VUS	4	5	69	11a	0
LB	0	0	14	4	1
B	0	0	5	17	2
Total Variants	19	8	96	32	3
Concordance Rate	53%	13%	72%	13%	67%

Shown are largest range of discordance across three laboratories.

^aIncludes four variants where the other two laboratories classified the variant as B and VUS, respectively