Table 2. Hazard Ratios and 95% CIs of Total and Site-Specific Cancers and Mortality by Randomized Vitamin D^a.

Disease outcome	No. of events		HR (95% CI)	P value
	Vitamin D (N = 12 927)	Placebo (N = 12 944)
Confirmed cancer
Total invasive	793	824	0.96 (0.88-1.06)	.47
Breast	124	122	1.02 (0.79-1.31)	.90
Prostate	192	219	0.88 (0.72-1.07)	.19
Colorectal	51	47	1.09 (0.73-1.62)	.67
Lung	74	74	1.00 (0.73-1.38)	.99
Confirmed metastatic cancer of any type	88	111	0.80 (0.60-1.05)	.11
Total cancer mortality	154	187	0.83 (0.67-1.02)	.08
Confirmed metastatic cancer or cancer death of any type	226	274	0.83 (0.69-0.99)	.04
Excluding 1 y	193	235	0.82 (0.68-1.00)	.047
Excluding 2 y	147	181	0.81 (0.66-1.01)	.07

Abbreviation: HR, hazard ratio.

^aAnalyses were from Cox regression models that were controlled for age, sex, and omega-3 fatty acid randomization group. Analyses were not adjusted for multiple comparisons. Analyses were done as intention-to-treat over all years of follow-up.