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. 2020 Nov 18;3(11):e2025850. doi: 10.1001/jamanetworkopen.2020.25850

Table 3. Vitamin D, Total Metastatic and Cancer Mortality Hazard Ratios and 95% Confidence Intervals by BMI Categoriesa.

BMI category Total No. No. events in groups Hazard ratio P value for interaction
Vitamin D Placebo HR (95% CI) P value
Total metastatic cancer and cancer mortality (n = 25 254)
<25 7843 58 96 0.62 (0.45-0.86) .004 .03
25 to <30 10 122 98 109 0.89 (0.68-1.17) .42
≥30 7289 65 61 1.05 (0.74-1.49) .79
Total metastatic cancer (n = 25 254)
<25 7843 24 39 0.63 (0.38-1.05) .08 .21
25 to <30 10 122 37 46 0.80 (0.52-1.23) .31
≥30 7289 25 24 1.03 (0.59-1.80) .92
Cancer mortality (n = 25 254)
<25 7843 38 68 0.58 (0.39-0.86) .007 .02
25 to <30 10 122 66 74 0.89 (0.64-1.23) .472
≥30 7289 46 39 1.15 (0.75-1.76) .518

Abbreviations: BMI, body mass index; HR, hazard ratio.

a

Analyses were from Cox regression models that were controlled for age, sex, and omega-3 fatty acid randomization group. Analyses were not adjusted for multiple comparisons.