Table 3. Vitamin D, Total Metastatic and Cancer Mortality Hazard Ratios and 95% Confidence Intervals by BMI Categoriesa.
BMI category | Total No. | No. events in groups | Hazard ratio | P value for interaction | ||
---|---|---|---|---|---|---|
Vitamin D | Placebo | HR (95% CI) | P value | |||
Total metastatic cancer and cancer mortality (n = 25 254) | ||||||
<25 | 7843 | 58 | 96 | 0.62 (0.45-0.86) | .004 | .03 |
25 to <30 | 10 122 | 98 | 109 | 0.89 (0.68-1.17) | .42 | |
≥30 | 7289 | 65 | 61 | 1.05 (0.74-1.49) | .79 | |
Total metastatic cancer (n = 25 254) | ||||||
<25 | 7843 | 24 | 39 | 0.63 (0.38-1.05) | .08 | .21 |
25 to <30 | 10 122 | 37 | 46 | 0.80 (0.52-1.23) | .31 | |
≥30 | 7289 | 25 | 24 | 1.03 (0.59-1.80) | .92 | |
Cancer mortality (n = 25 254) | ||||||
<25 | 7843 | 38 | 68 | 0.58 (0.39-0.86) | .007 | .02 |
25 to <30 | 10 122 | 66 | 74 | 0.89 (0.64-1.23) | .472 | |
≥30 | 7289 | 46 | 39 | 1.15 (0.75-1.76) | .518 |
Abbreviations: BMI, body mass index; HR, hazard ratio.
Analyses were from Cox regression models that were controlled for age, sex, and omega-3 fatty acid randomization group. Analyses were not adjusted for multiple comparisons.