Table 4.
Hazard ratio | p | 1-year expected events (SE) | 3-year expected events (SE) | |
---|---|---|---|---|
Age (per decade) | 0.8 | 0.293 | ||
22-year | 0.08 (0.02) | 0.39 (0.04) | ||
46-year | 0.05 (0.01) | 0.23 (0.06) | ||
Sex | 0.897 | 0.866 | ||
Male | 0.06 (0.01) | 0.26 (0.08) | ||
Female | 0.07 (0.02) | 0.29 (0.11) | ||
Duration of ITP (years) | 0.726 (per 1 log year) | 0.198 | ||
1-year | 0.07 (0.007) | 0.33 (0.04) | ||
6-year | 0.04 (0.01) | 0.19 (0.06) | ||
Prior therapy | 0.879 | 0.845 | ||
≤3 prior lines of therapy | 0.07 (0.02) | 0.3 (0.09) | ||
>3 prior lines of therapy | 0.06 (0.02) | 0.26 (0.1) | ||
Splenectomy | 1.375 | 0.689 | ||
Yes | 0.06 (0.006) | 0.27 (0.02) | ||
No | 0.08 (0.04) | 0.37 (0.18) | ||
Hemoglobin (g/dL) | 1.243 | 0.144 | ||
11.7 | 0.03 (0.009) | 1.77 (0.06) | ||
14.9 | 0.09 (0.02) | 1.42 (0.12) | ||
WBC (/μL) | 1.125 (per 1000 WBC/μL ) | 0.3 | ||
6700 | 0.05 (0.009) | 0.23 (0.04) | ||
10000 | 0.07 (0.009) | 0.34 (0.05) | ||
Paltelets | 1.016 (per 1000 platelets/μL) | 0.627 | ||
≤5000 | 0.05 (0.02) | 0.25 (0.07) | ||
17000 | 0.07 (0.01) | 0.32 (0.06) |