Table 4.
Factors associated the magnitude of anemia and undernutrition in HIV-infected children within one year of HAART initiation using GEE model
| Factors associated with magnitude of anemia from baseline to 12 months of ART initiation | |||||||
|
| |||||||
| Variables | Crude model | Adjusted model | |||||
|
|
|
||||||
| B (95% CI) | COR (95% CI) | P-value | Adjusted B (95% CI) | AOR (95% CI) | p-value | ||
|
| |||||||
| Sex | Male | 0 | 1 | 0 | 1 | ||
| Female | -0.38 (-0.88, 0.12) | 0.68 (0.42, 1.13) | 0.141 | -0.44 (-0.95, 0.08) | 0.65 (0.39, 1.08) | 0.095 | |
| Child residence | Urban | 0 | 1 | ||||
| Rural | -0.18 (-0.613, 0.974) | 1.20 (0.54, 2.65) | 0.656 | - | - | - | |
| Baseline WHO clinical stage | Stage I | 0 | 1. | 0 | 1 | ||
| Stage II, III and IV | 0.59 (0.04, 1.14) | 1.81 (1.04, 3.13) | 0.035 | 0.55 (0.02, 1.10) | 1.73 (1.02, 3.0) | 0.048 | |
| Baseline Functional status | Appropriate/working | 0 | 1. | - | - | ||
| Ambulatory or regression | -0.07 (-0.58, 0.43) | 0.93 (0.56, 1,54) | 0.775 | - | - | - | |
| Age at enrolment (month) | Continuous as a covariate | -0.04 (-0.02, 0.005) | 0.96 (0.98, 1.005) | 0.241 | -0.03 (-0.05, -0.001) | 0.97 (0.95, 0.99) | 0.026 |
| Baseline CD4 count | Continuous as a covariate | -0.001 (-0.002, 0.001) | 1.0 (0.998, 1.001) | 0.239 | -0.05 (-0.07, -0.02) | 0.95 (0.93, 0.98) | <0.01 |
|
| |||||||
| Factors associated with magnitude of undernutrition from baseline to 12 months of ART initiation | |||||||
|
| |||||||
| Sex | Male | 0 | 1 | ||||
| Female | 0.045 (-0.359, 0.449) | 1.05 (0.7, 1.57) | 0.827 | - | - | - | |
| Child residence | Urban | 0 | 1 | ||||
| Rural | -0.07 (-0.685, 0.545) | 0.932 (0.50, 1.72) | 0.823 | - | - | - | |
| Baseline WHO clinical stage | Stage I | 0 | 1 | ||||
| Stage II, III and IV | 0.399 (-0.022, 0.819) | 1.49 (0.98, 2.27) | 0.063 | 0.003 (-0.001, 0.006) | 1.003 (0.99, 1.01) | 0.693 | |
| Baseline Functional status | Appropriate/working | 0 | 1 | ||||
| Ambulatory or regression | 0.083 (-0.317, 0.483) | 1.09 (0.73, 1.62) | 0.685 | - | - | - | |
| Age at enrolment (month) | Continuous as a covariate | -0.004 (-0.011, 0.003) | 0.996 (0.989, 1.003) | 0.222 | .004 (-0.012, 0.003) | 0.99 (0.98, 1.003) | 0.221 |
| Baseline CD4 count | Continuous as a covariate | -0.003 (-0.004, 0.001) | 0.997 (0.995, 1.001) | 0.229 | 0.002 (-0.004, 0.001) | 1.002 (0.99, 1.01) | 0.693 |
AOR: Adjusted odds ratio; B: Beta Coefficient; COR: Crude odds Ration; Italicized P-value in adjusted model shows a significant at P<0.05.