Table 1.
Risk factors associated with BKV-HC development
Risk factor | Increased risk | Decreased risk | Reference |
---|---|---|---|
Type of transplantation | Allogeneic especially after haploidentical | Autologous | [9,54,93] |
Type of donor | Unrelated donor | Matched or mismatched related donor | [9,13,54] |
Stem cell source | Cord blood or peripheral blood | Bone marrow | [9] |
Age of transplant | >7 years | <7 years | [9] |
Conditioning regimen | Myeloablative | Reduced intensity | [9,13,21,54] |
BK viruria | Urine BKV load >107 gEq/ml | - | [9,13,93] |
BK viraemia | Blood BKV load >103 gEq/ml | - | [9] |
Acute GVHD | Grade II-IV | - | [9] |