Table 1.

Summary of the case report

Case description	A 32-year-old woman with cardiac valve disease and spherocytosis, diagnosed with COVID-19. Systemic microvascular reactivity assessed with cutaneous laser doppler perfusion monitoring, with thermal hyperemia
First microcirculation test	Performed in the worst day of clinical evolution-severely impaired microvascular vasodilation, compared to a healthy control
Second microcirculation test	Performed after clinical and laboratory improvement-marked increase in baseline microvascular flow and endothelial-dependent vasodilation