Table 2. Carotid Artery MRI Plaque Burden Variables and Categorical Plaque Characteristics for the Incident CVD Analyses^a.

Variable	Median (IQR)		P value
	Incident CVD events (n = 172)	No incident CVD events (n = 1084)
Measures of MRI carotid artery plaque burden
Total wall volume, mL	0.43 (0.34-0.59)	0.40 (0.32-0.51)	.004
Carotid artery
Lumen area, mm2	0.39 (0.25-0.54)	0.43 (0.31-0.54)	.02
Wall area, mm2	0.35 (0.27-0.51)	0.32 (0.25-0.44)	.009
Normalized wall index	0.48 (0.36-0.62)	0.43 (0.34-0.55)	.001
Maximum carotid artery wall thickness, mm	2.22 (1.37-3.52)	1.96 (1.29-2.85)	.009
Maximum stenosis, %	5 (0-22)	0 (0-13)	<.001
Categorical MRI carotid artery plaque characteristics, No. (%)
Lipid core
Present	76 (44.19)	327 (30.17)	<.001
Present in ≥2 slices	66 (38.37)	272 (25.09)	<.001
Calcification present	67 (38.95)	309 (28.51)	.005
Intraplaque hemorrhage present	17 (9.88)	51 (4.70)	.005
Categorical plaque components, No. (%)
Lipid core plus calcification	37 (21.51)	146 (13.47)	<.001
Lipid core plus IPH	6 (3.49)	7 (0.65)
Calcification plus IPH	1 (0.58)	10 (0.92)
Lipid core plus calcification plus IPH	9 (5.23)	31 (2.86)

Abbreviations: CVD, cardiovascular disease; IPH, intraplaque hemorrhage; IQR, interquartile range; MRI, magnetic resonance imaging.

^aContinuous variables were analyzed; a 2-sample Wilcoxon rank sum test was used for nonnormal variables. Group differences for categorical variables were analyzed with the χ² or Fisher exact test.