TABLE 2.
Univariable and multivariable logistic regression on the factors associated with the elevation of alanine aminotransferase
| Characteristic | n | Univariable | Multivariable | ||
|---|---|---|---|---|---|
| OR (95% CI) | P‐value | OR (95% CI) | P‐value | ||
| Age (years) | 60 | 1.00 (0.97–1.04) | 0.86 | ||
| Sex | |||||
| Male | 43 | Reference | |||
| Female | 17 | 0.27 (0.07–1.02) | 0.05 | ||
| Bodyweight (kg) | 60 | 1.09 (1.02–1.15) | 0.01 | ||
| Height (cm) | 60 | 1.06 (0.97–1.16) | 0.17 | ||
| BMI (kg/m2) | 60 | 1.31 (1.00–1.72) | 0.05 | ||
| BT (°C)† | 60 | 1.61 (0.72–3.60) | 0.25 | ||
| SpO2 (%)‡ | 60 | 0.68 (0.50–0.94) | 0.02 | ||
| ALP (U/L)† | 60 | 1.01 (1.00–1.01) | 0.03 | ||
| γGTP (U/L)† | 60 | 1.03 (0.99–1.07) | 0.09 | ||
| LDH (U/L)† | 60 | 1.01 (1.00–1.01) | 0.07 | ||
| Albumin (g/dL)‡ | 60 | 0.41 (0.13–1.29) | 0.13 | ||
| Total bilirubin (mg/dL)† | 60 | 6.64 (0.86–51.12) | 0.07 | ||
| CRP (mg/dL)† | 60 | 1.17 (1.01–1.35) | 0.04 | ||
| Ferritin† (log10 ng/mL) | 59 | 16.49 (1.94–140.11) | 0.01 | ||
| PT‐INR | 58 | 3.74 (0.001–10 357) | 0.74 | ||
| Fibrinogen (mg/dL) | 58 | 1.01 (1.00–1.01) | 0.02 | ||
| FDP elevated | 33 | 4.89 (1.52–15.70) | 0.008 | ||
| not elevated (<2.5 μg/mL) | 25 | Reference | |||
| D‐dimer elevated | 24 | 6.97 (1.99–24.44) | 0.002 | 6.01 (1.19–30.43) | 0.03 |
| not elevated (<1.0 μg/mL) | 34 | Reference | Reference | ||
| BUN (mg/dL)† | 60 | 0.93 (0.78–1.10) | 0.38 | ||
| Creatinine (mg/dL)† | 60 | 1.00 (0.07–14.95) | 1.00 | ||
| White blood cell (×100/μL)† | 60 | 1.07 (1.02–1.12) | 0.004 | 1.06 (1.01–1.12) | 0.03 |
| Lymphocyte count (/μL)‡ | 60 | 1.00 (1.00–1.00) | 0.74 | ||
| Platelet (×10 000/μL) ‡ | 60 | 1.06 (0.99–1.15) | 0.10 | ||
| Hemoglobin (g/dL)‡ | 60 | 1.24 (0.87–1.76) | 0.23 | ||
†Maximum or ‡minimum value during hospitalization.
γGTP, γ‐glutamyl transpeptidase; ALP, alkaline phosphatase; BMI, body mass index; BT, body temperature; BUN, blood urea nitrogen; CRP, C‐reactive protein; FDP, fibrin/fibrinogen degradation products; LDH, lactase dehydrogenase; PT‐INR, prothrombin time international normalized ratio; SpO2, percutaneous saturation of oxygen.