TABLE 3.
Univariable and multivariable logistic regression on the factors associated with the elevation of alanine aminotransferase, excluding those with radiologically confirmed fatty liver
| Characteristic | n | Univariable | Multivariable | ||
|---|---|---|---|---|---|
| OR (95% CI) | P‐value | OR (95% CI) | P‐value | ||
| Age (years) | 47 | 1.02 (0.97–1.07) | 0.45 | ||
| Sex | |||||
| Male | 32 | Reference | |||
| Female | 15 | 0.22 (0.05–0.94) | 0.04 | ||
| Bodyweight (kg) | 47 | 1.11 (1.00–1.22) | 0.05 | ||
| Height (cm) | 47 | 1.11 (1.00–1.23) | 0.05 | ||
| BMI (kg/m2) | 47 | 1.35 (0.98–1.86) | 0.07 | ||
| BT (°C)† | 47 | 1.82 (0.83–4.01) | 0.14 | ||
| SpO2 (%)‡ | 47 | 0.68 (0.48–0.96) | 0.03 | ||
| ALP (U/L)† | 47 | 1.01 (1.00–1.01) | 0.007 | ||
| γGTP (U/L)† | 47 | 1.03 (0.99–1.07) | 0.20 | ||
| LDH (U/L)† | 47 | 1.01 (1.00–1.01) | 0.09 | ||
| Albumin (g/dL)‡ | 47 | 0.19 (0.03–1.02) | 0.05 | ||
| Total bilirubin (mg/dL)† | 47 | 3.30 (0.25–43.7) | 0.37 | ||
| CRP (mg/dL)† | 47 | 1.21 (0.99–1.48) | 0.07 | ||
| Ferritin† (log10 ng/mL) | 46 | 19.5 (0.83–463.0) | 0.07 | ||
| PT‐INR | 44 | 20.2 (0.002–217 742) | 0.53 | ||
| Fibrinogen (mg/dL) | 45 | 1.01 (1.00–1.01) | 0.04 | ||
| FDP elevated | 27 | 8.5 (1.96–36.8) | 0.004 | ||
| not elevated (<2.5 μg/mL) | 18 | Reference | |||
| D‐dimer elevated | 20 | 12.0 (2.53–56.9) | 0.002 | 13.0 (5.28x10−10‐3.19x1011) | 0.83 |
| not elevated (<1.0 μg/mL) | 25 | Reference | Reference | ||
| BUN (mg/dL)† | 47 | 0.94 (0.78–1.14) | 0.52 | ||
| Creatinine (mg/dL)† | 47 | 1.31 (0.09–19.8) | 0.85 | ||
| White blood cell (×100/μL)† | 47 | 1.07 (1.02–1.13) | 0.008 | 1.06 (0.65–1.73) | 0.81 |
| Lymphocyte count (/μL)‡ | 47 | 1.00 (1.00–1.00) | 0.75 | ||
| Platelet (×10 000/μL)‡ | 47 | 1.05 (0.97–1.14) | 0.23 | ||
| Hemoglobin (g/dL)‡ | 47 | 1.05 (0.67–1.65) | 0.82 | ||
†Maximum or ‡minimum value during hospitalization.
γGTP, γ‐glutamyl transpeptidase; ALP, alkaline phosphatase; BMI, body mass index; BT, body temperature; BUN, blood urea nitrogen; CRP, C‐reactive protein; FDP, fibrin/fibrinogen degradation products; LDH, lactase dehydrogenase; PT‐INR, prothrombin time international normalized ratio; SpO2, percutaneous saturation of oxygen.