TABLE 3.
Sensitivity, specificity, positive and negative predictive values, and AUCs for different score cutoffs of the LOW‐HARM score
| Cutoff | Se,a % | Sp, % | PPV, % | NPV, % | AUC (95% CI) |
|---|---|---|---|---|---|
| 0 | 100 | 0 | – | – | – |
| 5 | 99.5 | 64 | 73 | 99 | 0.82 (0.79–0.89) |
| 10 | 99 | 78.5 | 82 | 99 | 0.89 (0.86–0.92) |
| 15 | 96 | 81 | 83.5 | 95 | 0.89 (0.85–0.92) |
| 20 | 92.5 | 85 | 86 | 92 | 0.89 (0.86–0.92) |
| 25 | 91.5 | 89 | 90 | 91 | 0.90 (0.87–0.93) |
| 30 | 85.5 | 89.5 | 89 | 86 | 0.87 (0.84–0.91) |
| 35 | 82 | 92 | 91 | 84 | 0.87 (0.84–0.90) |
| 40 | 82 | 92 | 91 | 84 | 0.87 (0.84–0.91) |
| 45 | 77 | 94 | 93 | 80 | 0.86 (0.82–0.89) |
| 50 | 75.5 | 94.5 | 93 | 79.5 | 0.85 (0.82–0.88) |
| 55 | 69.5 | 95 | 93 | 76 | 0.82 (0.79–0.86) |
| 60 | 68.5 | 95.5 | 94 | 75 | 0.82 (0.78–0.86) |
| 65 | 63 | 97.5 | 96 | 72.5 | 0.80 (0.77–0.84) |
| 70 | 58 | 98 | 97 | 70 | 0.78 (0.74–0.82) |
| 75 | 57 | 98 | 96.5 | 69.5 | 0.78 (0.74–0.81) |
| 80 | 51 | 99 | 98 | 67 | 0.75 (0.71–0.79) |
| 85 | 43.5 | 99.5 | 99 | 64 | 0.72 (0.68–0.75) |
| 90 | 35 | 99.5 | 99 | 60.5 | 0.67 (0.64–0.71) |
| 95 | 23.5 | 100 | 100 | 56.5 | 0.62 (0.59–0.65) |
| 100 | 0 | 100 | – | – | – |
AUC, area under the receiver operating characteristic curve; NPV, negative predictive value; PPV, positive predictive value; Se, sensitivity; Sp, specificity.
aPositivity defined as having a score above the cutoff value and dying.