TABLE 1.
Admission Clinical and Laboratory Characteristics
| Characteristics | Liver Injury Cohort (AST or ALT ≥3 times ULN) (n = 109) | Control Cohort (Normal AST/ALT) (n = 67) | P |
|---|---|---|---|
| Age, years | 61 (53, 69) | 62 (51, 80) | 0.14 |
| Sex, n (%) | <0.001 | ||
| Male | 78 (71.6%) | 25 (37.3%) | |
| Female | 31 (28.4%) | 42 (62.7%) | |
| Race, n (%) | 0.02 | ||
| White | 24 (22.2%) | 30 (46.2%) | |
| Black | 25 (23.2%) | 10 (15.4%) | |
| Asian | 8 (7.4%) | 2 (3.0%) | |
| Unknown | 51 (47.2%) | 23 (35.4%) | |
| Ethnicity | |||
| Hispanic | 33 (30.3%) | 22 (32.8%) | 0.92 |
| BMI | 28.4 (25.4, 32.9) | 26.9 (24.2, 31.6) | 0.16 |
| Comorbidities, n (%) | |||
| Chronic cardiac disease | 13 (11.9%) | 15 (22.4%) | 0.07 |
| Chronic pulmonary disease | 20 (18.4%) | 16 (23.9%) | 0.38 |
| Chronic kidney disease | 13 (11.9%) | 19 (28.4%) | 0.006 |
| Chronic neurologic disease | 10 (9.2%) | 7 (10.5%) | 0.78 |
| Cancer | 14 (12.8%) | 7 (10.5%) | 0.63 |
| HIV | 1 (0.9%) | 1 (1.5%) | 0.73 |
| DM | 36 (33.0%) | 39 (58.2%) | 0.001 |
| HTN | 48 (44.0%) | 36 (53.7%) | 0.21 |
Values expressed as median (IQR) unless otherwise stated; ULN defined as 40 U/L.
Abbreviations: BMI, body mass index; DM, diabetes mellitus; HIV, human immunodeficiency virus; HTN, hypertension.