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. 2020 Oct 20;234(11):1223–1234. doi: 10.1177/0954411920964630

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© IMechE 2020

This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 5. — Coronal slices of the 6-MPET solution fields allied to (a) perfusion, (b) clearance of CSF/ECF and (c) paravenous filtration velocity. Some quantitative similarities for these solution fields can be found in Vardakis et al., Croci et al. and Thomas.^48,65,66 It can be seen that the impact of the cerebroventricular geometry (in terms of its concavity) influences the localisation of the areas of peak perfusion, paravenous filtration, and clearance of CSF/ECF. These areas could play a role in AD progression.