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. 2020 Nov 18;11:5881. doi: 10.1038/s41467-020-19589-w

Fig. 3. Imidazole propionate is associated with an unhealthy diet, but not histidine intake.

Fig. 3

a Dietary histidine intake according to quartiles of imidazole propionate. P-values were calculated with linear regression adjusted for age, gender, body mass index, ethnicity, diabetes status, creatinine clearance, daily energy intake (kcal/day), and enrollment center. Data are represented as boxplots: middle line is the median, the lower and upper hinges are the first and third quartiles, the upper whisker extends from the hinge to the largest value no further than 1.5× the interquartile range (IQR) from the hinge, and the lower whisker extends from the hinge to the smallest value at most 1.5× IQR of the hinge. Gray dots are single data points. b Correlation matrix for imidazole propionate serum levels and macronutrients, food categories and dietary scores [the alternate Healthy Eating Index (aHEI), Dietary Approaches to Stop Hypertension (DASH) score, dietary diversity score (DDS) and Mediterranean diet score]. Pearson partial correlation coefficients and P-values were calculated using partial correlations adjusted for age, gender, body mass index, ethnicity, diabetes status, creatinine clearance, daily energy intake (kcal/day), and enrollment center. *P < 0.05, **False discovery rate (FDR) adjusted P < 0.05. See Supplementary Table 8. Source data are provided as a Source Data file.