Skip to main content
. 2020 Nov 19;106:104488. doi: 10.1016/j.bioorg.2020.104488

Fig. 22.

Fig. 22

Binding models of DSF into SARS-CoV-2 main protease, 3CLpro. (a) Depiction of the overall structure showing the Cys145 and His41 catalytic residues located in the active site cavity and (b) SARS-CoV-2 3CLpro-DSF. [270]. Reprinted from Journal of Biomolecular Structure and Dynamics, N. Lobo-Galo, M. Terrazas-López, A. Martínez-Martínez, Á.G. Díaz-Sánchez. “FDA-approved thiol-reacting drugs that potentially bind into the SARS-CoV-2 main protease, essential for viral replication” with permission of Taylor & Francis Ltd. Copyright 2020.