Table 1.

Reported anti-coronavirus activity for CQ, HCQ and ADQ.

Drug	MERS-CoV (µM)	SARS-CoV-1 (µM)	SARS-CoV-2 (µM)
CQ diphosphate	EC50 = 6.275e[103]	IC50 = 8.8a[102]	IC50 = 46.80c[106]
	EC50 = 3.0b[104]	EC50 = 6.538f[103]	EC50 = 1.13d[69]
		EC50 = 4.1b[104]	EC50 = 5.47c[105]
HCQ sulfate	EC50 = 8.279e[103]	EC50 = 7.966f[103]	IC50 = 11.17c[106]
			EC50 = 0.72c[105]
ADQ dihydrochoride dihydrate	EC50 = 6.212e[103]	EC50 = 1.274f[103]	IC50 = 4.94c[106]

^aMOI not reported.

^bMOI = 0.005.

^cMOI = 0.01.

^dMOI = 0.05.

^eMOI = 0.1.

^fMOI = 1.0.