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. 2020 Nov 19;37(4):1349–1360. doi: 10.1007/s10554-020-02089-9

Table 1.

Previous reports about myocardial necrosis marker in COVID-19 patients

Patients with SARS-CoV-2 infection Patients with abnormal cardiac biomarkers Cardiac lesion biomarkers Notes
Xu et al. [16] 53 30

LDH

CK

Myo

TNT-HSST

NT-proBNP

This study shows that cardiac abnormalities including elevated myocardial enzyme levels (56.6%) are common in COVID-19 patients
Wu et al. [5] 188

Abnormal hs-TNI 11.2%

68.6% LDH abnormal

76.1% α-HBDH abnormal

Abnormal CK 11.2%

Abnormal CK-MB 10.1%

hs-TNI

CK

CK-MB

LDH

α-HBDH

This study assessed the associations between heart injury indicators and mortality in COVID-19 patients and that high hs-TnI on admission can be associated with higher mortality
Bo Zhou et al. [26] 34 Abnormal c-TNI 8/8 in very severe group and 1/26 in severy group

c-TNI

CK

LDH

α-HBDH

They found high percentage of increased cTnI levels in very severe COVID-19
Huang et al. [15] 41

Abnormal CK 13/40 (33%)

Abnormal hs-TNI 5/41 (12%)

Abnormal LDH 29/40 (73%)

LDH

CK

Hs-TNI

They report a cohort of 41 patients with laboratory confirmed 2019-nCoV infection
Chen et al. [29] 120

Abnormal c-TNI (n = 12, 10%)

Abnormal NT-proBNP (n = 33, 27.5%)

NT-proBNP

c-TNI

This study has shown condition of some patients with severe SARS-CoV-2 infection, patients might deteriorate rapidly a possible exitus was a fulminant myocarditis