Table 2.
Author | Year | HIV status | Type of non-TB controls | Technology (MIG) | Antigen (MIG) | Sensitivity (%) | Specificity (%) | AUC | TP | FP | FN | TN |
Manngo PM[11] | 2019 | 9 (8.65%) | Other respiratory diseases | Multiplex immunoassay | Unstimulated | 70 | 57 | 0.73 | 25 | 30 | 10 | 39 |
La Manna MP[12] | 2018 | None | Other respiratory diseases | Multiplex immunoassay | Stimulated | 94.44 | 90 | 0.8944 | 25 | 2 | 2 | 18 |
Jacobs R[13] | 2016 | 14 (25.5%) | Other respiratory diseases | Multiplex immunoassay | Unstimulated | 68 | 88 | 0.81 | 15 | 4 | 7 | 29 |
Kim S[14] | 2015 | None | Healthy controls | RT-PCR | Stimulated | 85.71 | 86.21 | - | 24 | 4 | 4 | 25 |
Chung W[15] | 2015 | None | Other respiratory diseases | ELISA | Unstimulated | 81.1 | 88.5 | 0.89 | 163 | 6 | 38 | 46 |
Lee K[16] | 2015 | None | Healthy controls | ELISA | Unstimulated | 89.3 | 89.1 | 0.935 | 147 | 28 | 18 | 228 |
Chung WY[17] | 2014 | None | Other respiratory diseases | ELISA | Stimulated | 88.6 | 87.9 | 0.941 | 140 | 7 | 18 | 51 |
Wang X[18] | 2012 | None | Healthy controls | Microbead-based assay | Stimulated | 85.4 | 80.8 | 0.896 | 152 | 30 | 26 | 126 |
AUC = area under curve, ELISA = enzyme-linked immunosorbent assay, FN = false negative, FP = false positive, HIV = human immunodeficiency virus, RT-PCR = reverse transcription-polymerase chain reaction, TB = tuberculosis, TN = true negative, TP = true positive.