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. 2020 Nov 19;15(11):e0242513. doi: 10.1371/journal.pone.0242513

Table 1. Summary of differences in developmental milestone findings for each ART regimen compared to control.

Days delay vs. control ATV/r/ABC/3TC ATV/r/TDF/FTC
Male Female Male Female
Negative geotaxis 2 days delay 2.5 days delay 2 days delay 2.5 days delay
Cliff aversion 2 days delay 2 days delay 2 days delay 2 days delay
Rooting 1 day delay No delay 1 day delay No delay
Outer ear opening No delay 0.5 day delay 0.5 day delay 0.5 day delay
Ear twitch No delay 1 day delay 1.5 days delay 1.5 days delay
Forelimb grasp No delay 1 day delay No delay No delay
Surface righting No delay No delay No delay No delay
Air righting No delay No delay No delay No delay
Auditory reflex No delay No delay No delay No delay
Open field traversal No delay No delay No delay No delay
Eyes opening No delay No delay No delay No delay
Incisors eruption No delay No delay No delay No delay
Fur appearance No delay No delay No delay No delay
Olfaction Deficit present No deficit No deficit No deficit

ATV/r, ritonavir-boosted atazanavir; ABC, abacavir; 3TC, lamivudine; TDF, tenofovir; FTC, emtricitabine.