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. 2020 Nov 19;15(11):e0242655. doi: 10.1371/journal.pone.0242655

Table 6. Clinical sensitivity and specificity.

Vibrant COVID-19 Ab Clinical Diagnosis–NP Swab Positive Total Analysis
Positive Controls (95% Confidence)
Overall IgG/IgA/IgM Positive 302 12 314 Sensitivity = 99.67% (98.15% - 99.94%)
Negative 1 5250 5251 Specificity = 99.77% (99.60% - 99.87%)
Total 303 5262 5565
Vibrant COVID-19 Ab Clinical Diagnosis–NP Swab Positive Total Analysis
Positive Controls (95% Confidence)
Overall IgG Positive 300 12 312 Sensitivity = 99.01% (97.13% - 99.66%)
Negative 3 5250 5253 Specificity = 99.77% (99.60% - 99.87%)
Total 303 5262 5565
Vibrant COVID-19 Ab Clinical Diagnosis–NP Swab Positive Total Analysis
Positive Controls (95% Confidence)
Overall IgA Positive 187 5 192 Sensitivity = 61.72% (56.13% - 67.01%)
Negative 116 5257 5373 Specificity = 99.90% (99.78% - 99.96%)
Total 303 5262 5565
Vibrant COVID-19 Ab Clinical Diagnosis–NP Swab Positive Total Analysis
Positive Controls (95% Confidence)
Overall IgM Positive 265 10 275 Sensitivity = 87.46% (83.25% - 90.73%)
Negative 38 5252 5290 Specificity = 99.81% (99.65% - 99.90%)
Total 303 5262 5565