Table 1. Demographic data of first-ever stroke patients.
|
First-ever ischemic stroke eGFR (ml/min/1.73 m2) |
Total |
G1 ≥90 |
G2 60–89 |
CKD G3 30–59 |
CKD G4 15–29 |
CKD G5 <15 |
p-value |
| Number | 9,878 | 3,372 | 3,957 | 1,943 | 309 | 297 | |
| Age, y/o | 67.1±13.2 | 60.9±13.0 | 68.7±12.2 | 73.8±11.2 | 74.1±11.8 | 66.8±12.6 | <.0001 |
| Male, n (%) | 5967 (60.4) | 2095 (62.1) | 2482 (62.7) | 1089 (56) | 156 (50.5) | 145 (48.8) | <.0001 |
| Admission NIHSS | 5.9±7.0 | 5.2±6.0 | 5.6±6.8 | 6.8±7.8 | 7.8±8.8 | 7.5±8.4 | <.0001 |
| Hypertension, n (%) | 7407 (75) | 2247 (66.6) | 2986 (75.5) | 1639 (84.4) | 272 (88.0) | 263 (88.6) | <.0001 |
| Atrial fibrillation, n (%) | 1339 (13.6) | 276 (8.2) | 578 (14.6) | 379 (19.5) | 68 (22.0) | 38 (12.8) | <.0001 |
| Other heart diseases, n (%) | 2744 (27.8) | 624 (18.5) | 1129 (28.5) | 747 (38.4) | 133 (43.0) | 111 (37.4) | <.0001 |
| Hyperlipidemia, n (%) | 3168 (32.1) | 1107 (32.8) | 1221 (30.9) | 647 (33.3) | 111 (35.9) | 82 (27.6) | 0.0452 |
| Diabetes mellitus, n (%) | 3683 (37.3) | 1155 (34.3) | 1309 (33.1) | 842 (43.3) | 187 (60.5) | 190 (64.0) | <.0001 |
| Smoking, n (%) | 3284 (33.2) | 1295 (38.4) | 1339 (33.8) | 511 (26.3) | 82 (26.5) | 57 (19.2) | <.0001 |
| Alcohol, n (%) | 1669 (16.9) | 741 (22.0) | 649 (16.4) | 227 (11.7) | 25 (8.1) | 27 (9.1) | <.0001 |
| Outcome | |||||||
| Mortality, n (%) | |||||||
| 1M | 230 (2.3) | 36 (1.1) | 76 (1.9) | 78 (4.0) | 21 (6.8) | 19 (6.4) | <.0001 |
| 12M | 885 (9.0) | 145 (4.3) | 298 (7.5) | 294 (15.1) | 70 (22.7) | 78 (26.3) | <.0001 |
| Discharge BI | 73.0±34.3 | 77.6±32.2 | 74.6±33.4 | 66.6±36.2 | 57.9±37.5 | 63.4±37.5 | <.0001 |
| Discharge mRS | 2.2±1.7 | 2.0±1.6 | 2.2±1.7 | 2.5±1.7 | 2.9±1.7 | 2.7±1.8 | <.0001 |
| Length of stay (days) | 10.9±12.5 | 10.1±13.8 | 10.5±10.8 | 12.1±12.5 | 13.5±13.9 | 14.0±15.4 | <.0001 |
|
First-ever hemorrhagic stroke eGFR (ml/min/1.73 m2) |
Total |
G1 ≥90 |
G2 60–89 |
CKD G3 30–59 |
CKD G4 15–29 |
CKD G5 <15 |
p-value |
| Number | 1,386 | 560 | 491 | 204 | 43 | 88 | |
| Age, y/o | 60.5±14.3 | 56.8±13.5 | 61.9±14.4 | 66.3±14.2 | 63.3±14.3 | 60.7±13.2 | <.0001 |
| Male, n (%) | 910 (65.7) | 368 (65.7) | 332 (67.6) | 123 (60.3) | 33 (76.7) | 54 (61.4) | 0.1646 |
| Admission NIHSS | 15.3±13.9 | 13.9±12.9 | 14.5±13.8 | 17.3±14.8 | 17.5±15.0 | 23.0±15.2 | <.0001 |
| Hypertension, n (%) | 1155 (83.3) | 433 (77.3) | 422 (85.9) | 180 (88.2) | 40 (93) | 80 (90.9) | <.0001 |
| Atrial fibrillation, n (%) | 69 (5.0) | 18 (3.2) | 26 (5.3) | 19 (9.3) | 1 (2.3) | 5 (5.7) | 0.0133 |
| Other heart diseases, n (%) | 158 (11.4) | 44 (7.9) | 66 (13.4) | 35 (17.2) | 4 (9.3) | 9 (10.2) | 0.003 |
| Hyperlipidemia, n (%) | 178 (12.8) | 69 (12.3) | 75 (15.3) | 23 (11.3) | 5 (11.6) | 6 (6.8) | 0.1926 |
| Diabetes mellitus, n (%) | 292 (21.1) | 111 (19.8) | 82 (16.7) | 44 (21.6) | 19 (44.2) | 36 (40.9) | <.0001 |
| Smoking, n (%) | 559 (40.3) | 236 (42.1) | 193 (39.3) | 78 (38.2) | 19 (44.2) | 33 (37.5) | 0.7526 |
| Alcohol, n (%) | 484 (34.9) | 234 (41.8) | 167 (34.0) | 55 (27.0) | 13 (30.2) | 15 (17.0) | <.0001 |
| Outcome | |||||||
| Mortality | |||||||
| 1M | 211 (15.2) | 61 (10.9) | 63 (12.8) | 44 (21.6) | 7 (16.3) | 36 (40.9) | <.0001 |
| 12M | 319 (23.0) | 90 (16.1) | 100 (20.4) | 66 (32.4) | 12 (27.9) | 51 (58.0) | <.0001 |
| Discharge BI | 44.2±40.4 | 47.8±39.9 | 47±40.8 | 37.7±40.2 | 36.4±36.3 | 24.5±36.7 | <.0001 |
| Discharge mRS | 3.4±1.8 | 3.2±1.7 | 3.2±1.8 | 3.7±1.8 | 3.7±1.6 | 4.2±1.7 | <.0001 |
| Length of stay (days) | 16.2±16.3 | 16±16.7 | 15.7±15.1 | 16.4±15.6 | 21.2±20.5 | 16.8±18.9 | 0.3057 |
n (%) = number (%); M±SD = mean± standard deviation; BMI: body mass index; NIHSS: National Institute of Health Stroke Scale; eGFR: estimated glomerular filtration rate; BI: Barthel index; mRS: modified Ranking Scale