Skip to main content
. 2020 Nov 12;2020:6249375. doi: 10.1155/2020/6249375

Figure 4.

Figure 4

LTP response to different trains of the TBS protocol in Sprague-Dawley rats. As the number of TBS trains were increased, the LTP response increased in the SD rats. (a) Average input/output curves between stimulation voltage and fEPSP slope overlap for the study groups indicating no difference in basal synaptic excitability. (b) fEPSPs were enhanced compared to baseline following 2 trains of TBS (black, n = 8), 5 trains of TBS (green, n = 7), and 10 trains of TBS (blue, n = 6); as the number of trains were increased, the larger was the fEPSP increase. LTP response induced by 10 × TBS was significantly higher than both 2 × TBS and 5 × TBS throughout the whole 2-hour posttetanisation. Data are presented as means ± 95%confidenceintervals. Outsets above LTP curves represent average waveform field potentials during 30 min baseline prior to tetanisation and 0-30 min and 90-120 min posttetanisation. Horizontal bar: 1 mV; vertical bar: 5 ms. (c) PTP, STP, and LTP responses are presented as means ± 95%confidenceintervals. ∗pvalue < 0.05 and ∗∗pvalue < 0.01.