Table 4.
Secondary outcomes by group
| Secondary outcomes | Pregnant cases (n=38) |
Nonpregnant controls (n=94) |
Adjusted P value | Ratio of means (95% CI) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| N | Mean±SD | Median (IQR) | Range | N | Mean±SD | Median (IQR) | Range | |||
| Length of stay | ||||||||||
| Hospital length of stay (d) | 38 | 8.7±8.1 | 5.5 (4–10) | 2–42 | 94 | 7.1±8.2 | 5 (3–9) | 1–53 | .08 | 0.8 (0.6–1.0)b |
| ICU length of stay (d)a | 15 | 6.4±6.9 | 4 (1–9) | 0–26 | 16 | 9.3±11.8 | 5.5 (2–12) | 0–45 | –– | –– |
| n/N (%) | n/N (%) | Adjusted OR (95% CI) | ||
|---|---|---|---|---|
| ICU admission | 15/38 (39.5) | 16/94 (17.0) | <.01 | 5.2 (1.5–17.5) |
| Discharge disposition | .77 | |||
| Home without O2 requirement | 35/38 (92.1) | 77/94 (81.9) | Ref | |
| SNF or LTAC or home with O2 or other requirements | 3/38 (7.9) | 14/94 (14.9) | 0.8 (0.3–2.8) | |
| Morbidity during admission | ||||
| Any morbidity | 12/38 (31.6) | 20/94 (21.3) | .57 | 1.4 (0.4–5.0) |
| Sepsis | 2/38 (5.3) | 7/94 (7.4) | ||
| Cardiac arrest | 1/38 (2.6) | 3/94 (3.2) | ||
| ARDS | 6/38 (15.8) | 7/94 (7.4) | ||
| Ventilation | 10/38 (26.3) | 10/94 (10.6) | ||
| Tracheostomy | 3/38 (7.9) | 1/94 (1.1) | ||
| Blood product transfusion | 2/38 (5.3) | 1/94 (1.1) | ||
| AKI | 0/38 (0.0) | 3/94 (3.2) | ||
| Shock | 2/38 (5.3) | 4/94 (4.3) | ||
| Other morbidity | 0/38 (0.0) | 3/94 (3.2) |
AKI, acute kidney injury; ARDS, acute respiratory distress syndrome; CI, confidence interval; ICU, intensive care unit; IQR, interquartile range; LTAC, long-term acute care; OR, odds ratio; Ref, referend; SD, standard deviation; SNF, skilled nursing facility.
DeBolt et al. Severe and critical COVID-19 in pregnant vs nonpregnant controls. Am J Obstet Gynecol 2021.
a
ICU length of stay is only calculated for those 31 patients who were admitted to the ICU (15 pregnant cases and 16 nonpregnant controls)
b
Hospital length of stay was log transformed and modeled using linear regression. The beta coefficient for the cases was exponentiated to estimate the ratio of the geometric means.