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An NMDA receptor antagonist suppressed tremor in Aspa/Hcn1 double-knockout rats. The total duration (left) and intensity (right) of body tremor in Aspaem34Kyo/Hcn1em1Kyo double-knockout rats given LY341495 (A), NBQX (B), or d-CPPene (C). d-CPPene, an NMDA receptor antagonist, significantly suppressed both the duration and intensity of tremor throughout the observation period (60 min). *; P<0.05, **; P<0.01, ***; P<0.001.
