Table 2.

Serologic characteristics of different types of AIHA [3, 11, 74]

Type of AIHA	Antibody type	Typical DAT	RBC eluate	Antigen specifity	Antibody titre at 4 °C
Warm AIHA	IgG (rarely IgA or IgM)	IgG or IgG + C3	IgG	panreactive	–
CAD	IgM	C3	nonreactive	usually anti-Ia	usually > 1:500
PCH	biphasic IgG	C3	nonreactive	usually anti-P	< 1:64
Mixed AIHA	IgG, IgM	IgG + C3	IgG	usually lack specifity of warm IgG, cold antibody differentlyb	cold antibodies < 1:64
DIHA	Ig G	IgG or IgG + C3	IgG	often Rh-related	–

^asometimes anti-i, rarely anti-Pr

^banti I, anti-i or lack specificity