Table 1.
Raw data on 37 cases of isolated choroidal melanocytosis. Cases are listed in ascending order by age at initial evaluation in the Ocular Oncology Service. This series includes 11 cases reported in 2006 [1]. Those 11 cases are identified by the case numbers assigned to them in the 2006 publication in the second column of this table
| Case no. | Case no. in 2006 series | Age at 1st detection (year) | Age at 1st OOS exam (year) | Sex | Eye | LBD (mm) | SBD (mm) | Shape | Relevant associated ocular features | Systemic associations | Follow-up (mo) |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 1 | 2 months | 2 months | F | R | 28.0 | 15.5 | Circular-ovoid | None | None | 73.9 |
| 2 | 2 | 8 months | 8 months | F | L | 15.5 | 13.5 | Circular-ovoid | None | None | 176.4 |
| 3 | - | 2 | 2 | M | L | 6.0 | 5.0 | Circular-ovoid | None | None | - |
| 4 | - | 2 | 2 | M | L | 18.0 | 14.0 | Circular-ovoid | RB in fellow eye | None | 25.3 |
| 5 | - | 4 | 4 | F | R | 6.0 | 4.5 | Circular-ovoid | None | None | 4.9 |
| 6 | - | 5 | 7 | F | R | 37.0 | 23.5 | Irregular-geographic | None | None | 20.1 |
| 7 | - | 8 | 8 | M | L | 8.5 | 6.5 | Irregular-geographic | None | None | 74.9 |
| 8 | 3 | 8 | 8 | F | R | 16.0 | 10.5 | Circular-ovoid | None | None | - |
| 9 | - | 8 | 8 | F | L | 9.0 | 7.5 | Circular-ovoid | None | Linear sebaceous nevus | 99.6 |
| 10 | - | 9 | 9 | F | R | 26.0 | 18.0 | Irregular-geographic | None | None | 6.4 |
| 11 | - | 9 | 10 | F | R | 14.5 | 11.0 | Irregular-geographic | None | None | 14.8 |
| 12 | - | 11 | 11 | F | R | 13.0 | 9.0 | Irregular-geographic | None | None | 45.3 |
| 13 | - | 12 | 12 | F | L | 8.5 | 6.5 | Irregular-geographic | None | None | 0.9 |
| 14 | - | 12 | 12 | M | R | 10.0 | 9.0 | Circular-ovoid | None | None | 9.6 |
| 15 | 4 | 14 | 14 | F | R | 20.0 | 13.5 | Circular-ovoid | None | None | 26.4 |
| 16 | - | 14 | 15 | M | L | 28.0 | 21.0 | Irregular-geographic | None | None | 13.1 |
| 17 | 5 | 12 | 17 | F | R | 22.5 | 20.5 | Irregular-geographic | None | Café au lait spot | - |
| 18 | 6 | 17 | 17 | M | L | 13.0 | 9.5 | Irregular-geographic | None | None | 1.0 |
| 19 | - | 6 | 18 | F | R | 15.5 | 15.0 | Circular-ovoid | None | None | 141.9 |
| 20 | - | 23 | 24 | F | L | 13.5 | 10.0 | Circular-ovoid | None | None | 12.1 |
| 21 | - | 25 | 29 | F | L | 10.0 | 9.0 | Circular-ovoid | CN in fellow eye; FANNUMs both eyes | None | 166.8 |
| 22 | 7 | 33 | 33 | M | R | 13.0 | 8.5 | Irregular-geographic | None | None | 24.1 |
| 23 | - | 36 | 38 | F | L | 9.5 | 8.5 | Circular-ovoid | None | None | 24.1 |
| 24 | - | 18 | 40 | M | L | 19.0 | 9.5 | Irregular-geographic | sIUM IR & CH fellow eye; FANNUM ipsi. | Congenital deafness | - |
| 25 | - | 41 | 41 | M | R | 9.5 | 9.0 | Circular-ovoid | CMM arising in ICM | None | 182.1 |
| 26 | 8 | 28 | 41 | M | L | 9.0 | 7.0 | Circular-ovoid | None | None | - |
| 27 | 9 | 43 | 43 | F | L | 8.5 | 7.5 | Circular-ovoid | FANNUM ipsi. | None | 0.6 |
| 28 | - | 45 | 46 | M | R | 17.0 | 8.5 | Irregular-geographic | CMM in fellow eye | None | 39.9 |
| 29 | - | 41 | 50 | F | R | 32.0 | 18.0 | Irregular-geographic | NONE | None | 105.1 |
| 30 | - | 58 | 58 | M | L | 9.5 | 5.5 | Irregular-geographic | NONE | None | 36.2 |
| 31 | - | 64 | 64 | M | L | 16.0 | 13.5 | Irregular-geographic | CMM arising in ICM | None | 28.8 |
| 32 | 10 | 70 | 70 | F | L | 6.0 | 5.0 | Circular-ovoid | NONE | None | - |
| 33 | - | 71 | 71 | F | R | 5.5 | 4.5 | Circular-ovoid | NONE | None | 175.6 |
| 34 | - | 74 | 74 | M | R | 15.0 | 10.5 | Circular-ovoid | CN in fellow eye | None | 12.1 |
| 35 | - | 84 | 84 | F | L | 6.0 | 5.5 | Circular-ovoid | AMD dry in both eyes | None | 0.2 |
| 36 | 11 | 82 | 86 | M | L | 6.5 | 6.0 | Circular-ovoid | FANNUM ipsi. | None | - |
| 37 | - | 86 | 87 | F | R | 21.0 | 18.0 | Irregular-geographic | CMM arising in ICM | None | 25.4 |
Legend for terms, acronyms, and abbreviations that appear in table (alphabetical order): AMD, age-related macular degeneration; CH, choroid; CMM, choroidal malignant melanoma; CN, choroidal nevus; F, female; FANNUMs, focal aggregates of normal or near-normal uveal melanocytes in choroid [20]; ICM, isolated choroidal melanocytosis; ipsi., ipsilateral (i.e., involving same eye as isolated choroidal melanocytosis); IR, iris; L, left; LBD, largest basal diameter (arc length) of melanocytic choroidal lesion, estimated cartographically to nearest 0.5 mm; M, male; mm, millimeters; mo, months; no., number; OOS, ocular oncology service (private ophthalmology practice of authors JJA and ZMC); R, right; RB, retinoblastoma; sIUM, sectoral isolated uveal melanocytosis; SBD, smallest basal diameter (arc length) of melanocytic choroidal lesion, estimated cartographically to nearest 0.5 mm; shape, shape of melanocytic choroidal lesion, categorized either as circular-ovoid or irregular-geographic