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. 2020 Nov 19;3:687. doi: 10.1038/s42003-020-01407-0

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a Experimental setup for the K/BxN serum transfer arthritis (STA) mouse model. Representative time-lapse images (b) and quantification (c) of vascular leakage in the paws of Prss57+/+ and Prss57−/− littermates and neutrophil elastase-deficient (Elane−/−) mice. Data are presented as mean ± s.d.; n = 4 biological replicates per genotype; ****P < 0.0001; two-way ANOVA and Bonferroni post hoc test. Data shown are representative of at least three independent experimental repeats.