Table 1.
Complete cohort | Sjögren’s syndrome n=83 | NSCS n=65 |
Healthy donors n=12 |
Gender, F/M | 75/8 | 57/8 | 11/1 |
Age in years mean | 54 [55] (14.0) | 55 [56] (13.3) | 43 [44] (7.4) |
[median] (SD) | |||
Primary/ Secondary Sjogren’s syndrome |
74/9 | ||
Disease duration in years | 5.9 [3] (6.0) | 5.1 [3] (5.6) | |
Mean [median] (SD) | |||
ESSDAI | 5.5 [5] (4.9) | n/a | |
Mean [median] (SD) | |||
Anti-Ro | 59% | 0% | |
Positive of total | |||
Anti-La | 35% | 0% | |
Positive of total | |||
Rheumatoid factor | 51% | 11% | |
Positive of total | |||
Serum IgG (g/L) | 15.4 [14.0] (5.8) | 11.0 [11.1] (3.7) | |
Mean [median] (SD) | |||
Serum IgA (g/L) | 2.9 [2.3] (1.8) | 2.8 [2.5] (2.4) | |
Mean [median] (SD) | |||
Serum IgM (g/L) | 1.5 [1.1] (2.0) | 1.3 [1.1] (0.7) | |
Mean [median] (SD) | |||
Serum C3 (g/L) | 1.2 [1.2] (0.3) | 1.5 [1.3] (1.3) | |
Mean [median] (SD) | |||
Serum C4 (g/L) | 0.2 [0.2] (0.1) | 0.3 [0.3] (0.1) | |
Mean [median] (SD) | |||
Lymphocytes count (x109/L) | 1.6 [1.5] (0.6) | 2.2 [2.1] (0.8) | |
Mean [median] (SD) | |||
Treatments | |||
Hydroxychloroquine csDMARDs* |
35/83 8/83 |
||
Steroids | 5/83 |
*csDMARDs other than hydroxychloroquine.
csDMARDs, conventional synthetic disease-modifying antirheumatic drugs; ESSDAI, EULAR Sjogren's syndrome disease activity index; NSCA, non-specific chronic sialadenitis.