Table 6.
Comparison of CYP2C9*2 and CYP2C9*3 allele frequencies from various ethnic populations
| Population | n | Number of alleles | CYP2C9*2 frequency (P value) | CYP2C9*3 frequency (P value) | Reference |
|---|---|---|---|---|---|
| Asian | |||||
| Filipino | 99 | 198 | 0 | 1.0 | Present study |
| Indian | 89 | 178 | 4.5 (.0023) | 10.1 (<.001) | [9] |
| Malay | 183 | 366 | 1.0 (NS) | 3.0 (NS) | [18] |
| Japanese | 140 | 280 | 0 (NS) | 1.8 (NS) | [20] |
| Korean | 574 | 1148 | 0 (NS) | 1.1 (NS) | [21] |
| Chinese | 394 | 788 | 0.1 (NS) | 3.6 (NS) | [22] |
| African | |||||
| Ethiopian | 150 | 300 | 4.3 (.0023) | 2.3 (NS) | [19] |
| Caucasian | |||||
| Romanian | 332 | 664 | 11.3 (<.001) | 9.3 (<.001) | [8] |
| Italian | 157 | 314 | 11.0 (<.001) | 9.0 (<.001) | [19] |
| French | 151 | 302 | 15.0 (<.001) | 8.0 (<.001) | [22] |
| British | 100 | 200 | 12.5 (<.001) | 8.5 (<.001) | [25] |
| American | 100 | 200 | 8.0 (<.001) | 6.0 (.01) | [26] |
| Swedish | 430 | 860 | 10.7 (<.001) | 7.4 (<.001) | [27] |
P value was calculated using Fisher’s exact test; NS = not significant.