TABLE 1.
The baseline characteristics and indications for prenatal testing of 5000 samples.
| Anomaly on | Advanced maternal | Abnormal result on | Abnormal NIPT | |||
| Characteristics | ultrasonography | age | maternal serum screening | NIPT results | Othera | All |
| Numberb | 1055 | 1784 | 1199 | 515 | 709 | 5000 |
| Maternal age (years)c | 29.48 ± 4.18 | 37.65 ± 2.29 | 29.03 ± 3.57 | 31.38 ± 5.09 | 29.19 ± 3.04 | 32.04 ± 5.17 |
| Gestational age (weeks)c | 23.42 ± 3.40 | 20.74 ± 1.68 | 20.90 ± 1.30 | 21.04 ± 1.68 | 20.51 ± 1.38 | 21.28 ± 2.24 |
| Amniotic fluid (no.) | 1003 | 1774 | 1199 | 515 | 704 | 4941 |
| Chorionic villi (no.) | 39 | 8 | 0 | 0 | 4 | 44 |
| Cord blood (no.) | 13 | 2 | 0 | 0 | 1 | 15 |
aOther indications for prenatal testing include history of adverse pregnancy, parental genetic abnormalities, in vitro fertilization, medication use or toxic exposure during pregnancy, consanguineous marriages and parental anxiety.
bAs more than one indication may be associated with each sample, the total number of listed five groups is more than 5000.
cPlus-minus values are means ± SD.