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. 2020 Nov 6;7:586648. doi: 10.3389/fmed.2020.586648

Table 2.

Cross-tabulations of four fungal examination methods including KOH examination, fungal culture, histopathological examination, and ex vivo CLSM vs. combined gold standard of the first three mentioned methods.

Combined gold standard
Positive Negative Total
CROSS-TABULATION KOH EXAMINATION VS. COMBINED GOLD STANDARD
KOH native preparation Positive Count 20 0 20
% within combined gold standard 83.3% 0.0% 35.1%
Negative Count 4 33 37
% within combined gold standard 16.7% 100.0% 64.9%
Total Count 24 33 57
% within combined gold standard 100.0% 100.0% 100.0%
CROSS-TABULATION FUNGAL CULTURE VS. COMBINED GOLD STANDARD
Fungal culture Positive Count 11 0 11
% within combined gold standard 45.8% 0.0% 19.3%
Negative Count 13 33 46
% within combined gold standard 54.2% 100.0% 80.7%
Total Count 24 33 57
% within combined gold standard 100.0% 100.0% 100.0%
CROSS-TABULATION HISTOLOGY VS. COMBINED GOLD STANDARD
Histology Positive Count 11 0 11
% within combined gold standard 55.0% 0.0% 20.8%
Negative Count 9 33 42
% within combined gold standard 45.0% 100.0% 79.2%
Total Count 20 33 53
% within combined gold standard 100.0% 100.0% 100.0%
CROSS-TABULATION OF EX VIVO CLSM VS. COMBINED GOLD STANDARD
Ex vivo CLSM Positive Count 22 14 36
% within combined gold standard 91.7% 42.4% 63.2%
Negative Count 2 19 21
% within combined gold standard 8.3% 57.6% 36.8%
Total Count 24 33 57
% within combined gold standard 100.0% 100.0% 100.0%

CLSM, confocal laser scanning microscopy; KOH, potassium hydroxide; vs., versus.